Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli

Calpain mediates epithelial cell microvillar effacement by enterohemorrhagic Escherichia coli

A member of the attaching and effacing (AE) family of pathogens, enterohemorrhagic Escherichia coli (EHEC) induces dramatic changes to the intestinal cell cytoskeleton, including effacement of microvilli. Effacement by the related pathogen enteropathogenic E. coli (EPEC) requires the activity of the...

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Bibliographic Details
Main Authors: YuShuan eLai, Kathleen eRiley, Andrew eCai, John M Leong, Ira M. Herman
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Microbiology
Subjects:
Microvilli
attaching and effacing (AE) lesion
CaCo-2
Calpastat
calpastatin
Ezrin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00222/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00222/full

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