Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity

Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity

Oligonucleotides with an antiproliferative activity for human cancer cells have attracted attention over the past decades; many of them have a G-quadruplex structure (GQ), and a cryptic target. In particular, DNA oligonucleotide HD1, a minimal GQ, could inhibit proliferation of some cancer cell line...

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Bibliographic Details
Main Authors: Olga Antipova, Nadezhda Samoylenkova, Ekaterina Savchenko, Elena Zavyalova, Alexander Revishchin, Galina Pavlova, Alexey Kopylov
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
dna g-quadruplex oligonucleotide
nanoconstruct
antiproliferative activity
human cancer cell lines
Online Access:https://www.mdpi.com/1420-3049/24/19/3625

Internet

https://www.mdpi.com/1420-3049/24/19/3625

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