Dispensability of the SAC Depends on the Time Window Required by Aurora B to Ensure Chromosome Biorientation.

Aurora B and the spindle assembly checkpoint (SAC) collaborate to ensure the proper biorientation of chromosomes during mitosis. However, lack of Aurora B activity and inactivation of the SAC have a very different impact on chromosome segregation. This is most evident in Saccharomyces cerevisiae, si...

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Bibliographic Details
Main Authors: Marta Muñoz-Barrera, Isabel Aguilar, Fernando Monje-Casas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4682840?pdf=render