Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats
Ouabain increases vascular resistance and may induce hypertension by inhibiting the Na+ pump. The effects of 0.18 and 18 µg/kg, and 1.8 mg/kg ouabain pretreatment on the phenylephrine (PHE; 0.1, 0.25 and 0.5 µg, in bolus)-evoked pressor responses were investigated using anesthetized normotensive (co...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2001-08-01
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Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000800014 |