Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats
Ouabain increases vascular resistance and may induce hypertension by inhibiting the Na+ pump. The effects of 0.18 and 18 µg/kg, and 1.8 mg/kg ouabain pretreatment on the phenylephrine (PHE; 0.1, 0.25 and 0.5 µg, in bolus)-evoked pressor responses were investigated using anesthetized normotensive (co...
Main Authors: | L.V. Rossoni, V.D. Pinto, D.V. Vassallo |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2001-08-01
|
Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000800014 |
Similar Items
-
Role of the Ouabain-Binding Site of Na,K-ATPase in Saline Loading and DOCA-Salt Hypertension
by: Loreaux, Elizabeth L.
Published: (2008) -
Effects of ouabain on vascular reactivity
by: Vassallo D.V., et al.
Published: (1997-04-01) -
Hypertensive effects of the iv administration of picomoles of ouabain
by: A.S. Padilha, et al.
Published: (2011-09-01) -
Hypertensive effects of the iv administration of picomoles of ouabain
by: A.S. Padilha, et al.
Published: (2011-09-01) -
A low concentration of ouabain (0.18 µg/kg) enhances hypertension in spontaneously hypertensive rats by inhibiting the Na+ pump and activating the renin-angiotensin system
by: F.D.M. Siman, et al.
Published: (2010-08-01)