The effect of sodium nitrite infusion on renal function, brachial and central blood pressure during enzyme inhibition by allopurinol, enalapril or acetazolamide in healthy subjects: a randomized, double-blinded, placebo-controlled, crossover study

The effect of sodium nitrite infusion on renal function, brachial and central blood pressure during enzyme inhibition by allopurinol, enalapril or acetazolamide in healthy subjects: a randomized, double-blinded, placebo-controlled, crossover study

Abstract Background Sodium nitrite (NaNO2) causes vasodilation, presumably by enzymatic conversion to nitric oxide (NO). Several enzymes with nitrite reducing capabilities have been discovered in vitro, but their relative importance in vivo has not been investigated. We aimed to examine the effects...

Full description

Bibliographic Details
Main Authors: Jeppe B. Rosenbaek, Erling B. Pedersen, Jesper N. Bech
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Nephrology
Subjects:
Sodium nitrite
Enzyme inhibition
Natriuresis
Aquaresis
Central blood pressure
Online Access:http://link.springer.com/article/10.1186/s12882-018-1035-x

Internet

http://link.springer.com/article/10.1186/s12882-018-1035-x

Similar Items