Statins and Antimicrobial Effects: Simvastatin as a Potential Drug against Staphylococcus aureus Biofilm.

Statins are important lipid-lowering agents with other pleiotropic effects. Several studies have explored a possible protective effect of statins to reduce the morbidity and mortality of many infectious diseases. Staphylococcus aureus is one of the main pathogens implicated in nosocomial infections;...

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Bibliographic Details
Main Authors: Talita Signoreti Graziano, Maria Claudia Cuzzullin, Gilson Cesar Franco, Humberto Osvaldo Schwartz-Filho, Eduardo Dias de Andrade, Francisco Carlos Groppo, Karina Cogo-Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128098