Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation

Aging is thought to be associated with increased molecular damage, but representative markers vary across conditions and organisms, making it difficult to assess properties of cumulative damage throughout lifespan. We used nontargeted metabolite profiling to follow age-associated trajectories of &am...

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Bibliographic Details
Main Authors: Andrei S Avanesov, Siming Ma, Kerry A Pierce, Sun Hee Yim, Byung Cheon Lee, Clary B Clish, Vadim N Gladyshev
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02077