Long-Term Effects of a Classic Ketogenic Diet on Ghrelin and Leptin Concentration: A 12-Month Prospective Study in a Cohort of Italian Children and Adults with GLUT1-Deficiency Syndrome and Drug Resistant Epilepsy

Long-Term Effects of a Classic Ketogenic Diet on Ghrelin and Leptin Concentration: A 12-Month Prospective Study in a Cohort of Italian Children and Adults with GLUT1-Deficiency Syndrome and Drug Resistant Epilepsy

The classical ketogenic diet (cKD) is an isocaloric, high fat, very low-carbohydrate diet that induces ketosis, strongly influencing leptin and ghrelin regulation. However, not enough is known about the impact of a long-term cKD. This study evaluated the effects of a 12-month cKD on ghrelin and lept...

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Bibliographic Details
Main Authors: Ramona De Amicis, Alessandro Leone, Chiara Lessa, Andrea Foppiani, Simone Ravella, Stefano Ravasenghi, Claudia Trentani, Cinzia Ferraris, Pierangelo Veggiotti, Valentina De Giorgis, Anna Tagliabue, Alberto Battezzati, Simona Bertoli
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Nutrients
Subjects:
drug-resistant epilepsy
GLUT1-Deficiency Syndrome
ketogenic diet
leptin
ghrelin
Online Access:https://www.mdpi.com/2072-6643/11/8/1716

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