RIM1/2 in retinal ganglion cells are required for the refinement of ipsilateral axons and eye-specific segregation

Abstract Neural activity is crucial for the refinement of neuronal connections during development, but the contribution of synaptic release mechanisms is not known. In the mammalian retina, spontaneous neural activity controls the refinement of retinal projections to the dorsal lateral geniculate nu...

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Bibliographic Details
Main Authors: Ahlem Assali, Corentin Le Magueresse, Mohamed Bennis, Xavier Nicol, Patricia Gaspar, Alexandra Rebsam
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03361-0