Expression and purification of soluble single-chain Fv against human fibroblast growth factor receptor 3 fused with Sumo tag in Escherichia coli

Expression and purification of soluble single-chain Fv against human fibroblast growth factor receptor 3 fused with Sumo tag in Escherichia coli

Background: Overexpression or mutated activation of Fibroblast growth factor receptor 3 (FGFR3) is involved in the pathogenesis of many tumors. More and more studies focus on the potential usage of therapeutic antibodies against FGFR3. Results: In this study, a novel single-chain Fv (ScFv) against F...

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Bibliographic Details
Main Authors: Zixuan Liu, Jizhou Zhang, Hongqiong Fan, Ruofeng Yin, Zhong Zheng, Qian Xu, Qing Liu, Haiting He, Xiaofan Peng, XinXin Wang, Xiaokun Li, Yechen Xiao
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Electronic Journal of Biotechnology
Subjects:
Escherichia coli
Fibroblast growth factor receptor 3, Single-chain Fv antibody
Soluble expression
Sumo tag
Online Access:http://www.sciencedirect.com/science/article/pii/S071734581500069X

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http://www.sciencedirect.com/science/article/pii/S071734581500069X

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