Genetic immunisation by liver stage antigen 3 protects chimpanzees against malaria despite low immune responses.

BACKGROUND: The true interest of genetic immunisation might have been hastily underestimated based on overall immunogenicity data in humans and lack of parallelism with other, more classical immunisation methods. PRINCIPAL FINDINGS: Using malaria Liver Stage Antigen-3 (LSA-3), we report that genetic...

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Bibliographic Details
Main Authors: Pierre Daubersies, Benjamin Ollomo, Jean-Pierre Sauzet, Karima Brahimi, Blanca-Liliana Perlaza, Wijnand Eling, Hubert Moukana, Pierre Rouquet, Charles de Taisne, Pierre Druilhe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2441826?pdf=render