IL-1α Up-Regulates IL-6 Expression in Bovine Granulosa Cells via MAPKs and NF-κB Signaling Pathways

IL-1α Up-Regulates IL-6 Expression in Bovine Granulosa Cells via MAPKs and NF-κB Signaling Pathways

Background/Aims: IL-6 is one of the main cytokines in regulating ovarian follicular development and ovulation. However, the factors that regulate IL-6 expression in follicles are still unclear. The aim of this study was to elucidate the mechanisms underlying the effect of IL-1α on IL-6 expression in...

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Bibliographic Details
Main Authors: Meng Yang, Xurong Wang, Lei Wang, Xuezhi Wang, Jianxi Li, Zhiqiang Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
IL-6
Granulosa cells
IL-1α
MAPKs pathway
NF-κB pathway
Online Access:http://www.karger.com/Article/FullText/456091

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http://www.karger.com/Article/FullText/456091

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