Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives

The ability to engineer pharmaceuticals that target the signal-dependent interactions of signaling proteins should revolutionize drug development. One approach to the rational design of protein interaction inhibitors uses decoy peptides, i.e. segments of protein primary sequence, which are derived f...

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Bibliographic Details
Main Authors: Vladimir Y Toshchakov, Artur Javmen
Format: Article
Language:English
Published: SAGE Publishing 2020-01-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919844310