Constant compression decreases vascular bud and VEGFA expression in a rabbit vertebral endplate ex vivo culture model.

<h4>Summary of background data</h4>The vascular buds in the vertebral endplate (VEP) are the structural foundation of nutrient exchange in the intervertebral disc (IVD). VEGF is closely related to angiogenesis in the endplate and intervertebral disc degeneration (IDD).<h4>Objective...

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Bibliographic Details
Main Authors: Jia-Wen Zhan, Shang-Quan Wang, Min-Shan Feng, Xu Wei, Jie Yu, Xun-Lu Yin, Tao Han, Li-Guo Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234747