Seasonal variation in vitamin D₃ levels is paralleled by changes in the peripheral blood human T cell compartment.

It is well-recognized that vitamin D₃ has immune-modulatory properties and that the variation in ultraviolet (UV) exposure affects vitamin D₃ status. Here, we investigated if and to what extent seasonality of vitamin D₃ levels are associated with changes in T cell numbers and phenotypes. Every three...

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Bibliographic Details
Main Authors: Ai-Leng Khoo, Hans J P M Koenen, Louis Y A Chai, Fred C G J Sweep, Mihai G Netea, André J A M van der Ven, Irma Joosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3250425?pdf=render