Enhancement of Lymphangiogenesis In Vitro via the Regulations of HIF-1α Expression and Nuclear Translocation by Deoxyshikonin

The objectives of this study were to determine the effects of deoxyshikonin on lymphangiogenesis. Deoxyshikonin enhanced the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) to undergo time-dependent in vitro cord formation. Interestingly, an opposite result was observed...

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Bibliographic Details
Main Authors: Orawin Prangsaengtong, Jun Yeon Park, Akiko Inujima, Yoshiko Igarashi, Naotoshi Shibahara, Keiichi Koizumi
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/148297