DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID

Changes in DNA methylation are required for the formation of germinal centers (GCs), but the mechanisms of such changes are poorly understood. Activation-induced cytidine deaminase (AID) has been recently implicated in DNA demethylation through its deaminase activity coupled with DNA repair. We inve...

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Bibliographic Details
Main Authors: Pilar M. Dominguez, Matt Teater, Nyasha Chambwe, Matthias Kormaksson, David Redmond, Jennifer Ishii, Bao Vuong, Jayanta Chaudhuri, Ari Melnick, Aparna Vasanthakumar, Lucy A. Godley, F. Nina Papavasiliou, Olivier Elemento, Rita Shaknovich
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009213