NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma
Abstract Chromatin modifying enzymes are frequently mutated in cancer, resulting in widespread epigenetic deregulation. Recent reports indicate that inactivating mutations in the histone methyltransferase NSD1 define an intrinsic subtype of head and neck squamous cell carcinoma (HNSC) that features...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-017-17298-x |