Evidence for circulating cancer stem-like cells and epithelial–mesenchymal transition phenotype in the pleurospheres derived from lung adenocarcinoma using liquid biopsy

Lung cancer stem cells are supposed to be the main drivers of tumor initiation, maintenance, drug resistance, and relapse of the disease. Hence, identification of the cellular and molecular aspects of these cells is a prerequisite for targeted therapy of lung cancer. Currently, analysis of circulati...

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Bibliographic Details
Main Authors: Sheefa Mirza, Nayan Jain, Rakesh Rawal
Format: Article
Language:English
Published: IOS Press 2017-03-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317695915