Simultaneous determination of 9 CYP450 enzymes in human liver microsomes using LC-MS/MS
Objective To develop a liquid chromatography with tandem mass spectrometry (LC-MS/MS) to simultaneously detect the activities of 9 CYP450 enzymes in human liver microsomes in order to anticipate the possibility of drug-drug interactions. Methods Nine different enzyme substrates were used as probes t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Third Military Medical University
2021-02-01
|
| Series: | Di-san junyi daxue xuebao |
| Subjects: | |
| Online Access: | https://aammt.tmmu.edu.cn/Upload/rhtml/202008230.htm |