Expression analysis of combinatorial genes using a bi-cistronic T2A expression system in porcine fibroblasts.

In pig-to-primate xenotransplantation, multiple transgenic pigs are required to overcome a series of transplant rejections. The generation of multiple transgenic pigs either by breeding or the introduction of several mono-cistronic vectors has been hampered by the differential expression patterns of...

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Main Authors: Sunghoon Hurh, Bumrae Cho, Dong-Joo You, Hwajung Kim, Eun Mi Lee, Sang Hoon Lee, Sol Ji Park, Hayne Cho Park, Ok Jae Koo, Jaeseok Yang, Kook-Hwan Oh, Byeong Chun Lee, Jong-Ik Hwang, Curie Ahn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726604?pdf=render