Cancer Cell Response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs

Cancer Cell Response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs

A comprehensive proteome map of T-lymphoblastic leukemia cells and its alterations after daunorubicin, doxorubicin and mitoxantrone treatments was monitored and evaluated either by paired comparison with relevant untreated control and using multivariate classification of treated and untreated sample...

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Bibliographic Details
Main Authors: Jirina Tyleckova, Rita Hrabakova, Katerina Mairychova, Petr Halada, Lenka Radova, Petr Dzubak, Marian Hajduch, Suresh J. Gadher, Hana Kovarova
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
anthracycline/anthracenedione
T-lymphoblastic leukemia
proteomics
early anti-cancer response
adaptive cancer mechanisms
protein biosynthesis
ubiquitin-proteasome system
energy metabolism
transport proteins
tumor immunity
Online Access:http://www.mdpi.com/1422-0067/13/12/15536

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http://www.mdpi.com/1422-0067/13/12/15536

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