Molecular genetic characterization reveals linear tumor evolution in a pulmonary sarcomatoid carcinomas patient with a novel PHF20-NTRK1 fusion: a case report

Molecular genetic characterization reveals linear tumor evolution in a pulmonary sarcomatoid carcinomas patient with a novel PHF20-NTRK1 fusion: a case report

Abstract Background Pulmonary sarcomatoid carcinoma (SC) consists of both carcinomatous and sarcomatous tumors with high degree of malignancy, rapid progression, and poor prognosis. However, little is known regarding how pulmonary SC develops and progresses. Case presentation A 66-year-old male was...

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Bibliographic Details
Main Authors: Jianjun Ge, Bin Yao, Jia Huang, Xue Wu, Hua Bao, Qiuxiang Ou, Yang W. Shao, Jun Chen
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
Lung cancer
Pulmonary sarcomatoid carcinoma
Mutation profiling
Tumor evolution
NTRK1 fusion
Online Access:http://link.springer.com/article/10.1186/s12885-019-5780-4

Internet

http://link.springer.com/article/10.1186/s12885-019-5780-4

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