Hallmarks of human “immunosenescence”: adaptation or dysregulation?

<p>Abstract</p> <p>Is immunosenescence an intrinsic ageing process leading to dysregulation of immunity or an adaptive response of the individual to pathogen exposure? Age-associated differences in bone marrow immune cell output and thymic involution suggest the former. Accepted ha...

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Bibliographic Details
Main Author: Pawelec Graham
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Immunity & Ageing
Online Access:http://www.immunityageing.com/content/9/1/15