Tau and atrophy: domain-specific relationships with cognition

Abstract Background Late-onset Alzheimer’s disease (AD) is characterized by primary memory impairment, which then progresses towards severe deficits across cognitive domains. Here, we report how performance in cognitive domains relates to patterns of tau deposition and cortical thickness. Methods We...

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Bibliographic Details
Main Authors: Leonardino A. Digma, John R. Madsen, Emilie T. Reas, Anders M. Dale, James B. Brewer, Sarah J. Banks, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Tau
Online Access:http://link.springer.com/article/10.1186/s13195-019-0518-8