Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation

Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation

Long Interspersed Nuclear Element 1 (LINE-1) retrotransposons are the major repetitive elements in mammalian genomes. LINE-1s are well-accepted as driving forces of evolution and critical regulators of the expression of genetic information. Alterations in LINE-1 DNA methylation may lead to its aberr...

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Bibliographic Details
Main Authors: Isabelle R. Miousse, Jianhui Chang, Lijian Shao, Rupak Pathak, Étienne Nzabarushimana, Kristy R. Kutanzi, Reid D. Landes, Alan J. Tackett, Martin Hauer-Jensen, Daohong Zhou, Igor Koturbash
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
DNA methylation
hematopoietic cells
ionizing radiation
retrotransposons
Online Access:https://www.mdpi.com/1422-0067/18/7/1430

Internet

https://www.mdpi.com/1422-0067/18/7/1430

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