In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine.

In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine.

Brain-derived neurotrophic factor (BDNF) plays an important role in neurogenesis and synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs the function and distribution of BDNF. This mutation is related to several psychiatric disorders. The pro-region of BDNF, particu...

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Bibliographic Details
Main Authors: Clara Carolina Silva De Oliveira, Gabriel Rodrigues Coutinho Pereira, Jamile Yvis Santos De Alcantara, Deborah Antunes, Ernesto Raul Caffarena, Joelma Freire De Mesquita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215508

Internet

https://doi.org/10.1371/journal.pone.0215508

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