Sauchinone Blocks Ethanol Withdrawal-Induced Anxiety but Spares Locomotor Sensitization: Involvement of Nitric Oxide in the Bed Nucleus of the Stria Terminalis

Both the positive (manifested by locomotor sensitization) and negative (withdrawal symptoms) reinforcing effects of ethanol (EtOH) involve central nitric oxide (NO) signaling. Sauchinone (a bioactive lignan in Saururus chinensis) has been shown to improve methamphetamine-induced behavioral and neuro...

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Bibliographic Details
Main Authors: Yu Jiao, Sang Chan Kim, Yuhua Wang, Tong Wu, Haifeng Jin, Chul Won Lee, Sook Jahr Park, Bong Hyo Lee, Hee Young Kim, Chae Ha Yang, Zhenglin Zhao, Rongjie Zhao
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2021/6670212