I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice

I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice

Aortic stenosis (AS) is considered to be an actively regulated progress that involves similar pathophysiological processes as atherosclerosis. I-κB kinase-ε (IKKε) is a proinflammatory molecule involved in atherosclerosis. The objective of the present study was to define the role of IKKε in patholog...

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Bibliographic Details
Main Authors: Shuai He, Fulai Nian, Wen Chen, Li Yin, Merveesh L. Auchoybur, Zhonghao Tao, Shaowen Tang, Xin Chen
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Aortic stenosis
I-κB kinase-ε
Angiotensin II
Valve
Valvular remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218336473

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http://www.sciencedirect.com/science/article/pii/S0753332218336473

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