11q deletion in neuroblastoma: a review of biological and clinical implications

11q deletion in neuroblastoma: a review of biological and clinical implications

Abstract Deletion of the long arm of chromosome 11 (11q deletion) is one of the most frequent events that occur during the development of aggressive neuroblastoma. Clinically, 11q deletion is associated with higher disease stage and decreased survival probability. During the last 25 years, extensive...

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Bibliographic Details
Main Authors: Vid Mlakar, Simona Jurkovic Mlakar, Gonzalo Lopez, John M. Maris, Marc Ansari, Fabienne Gumy-Pause
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Cancer
Subjects:
Neuroblastoma
11q deletion
MYCN amplification
Cancer
Development
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12943-017-0686-8

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http://link.springer.com/article/10.1186/s12943-017-0686-8

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