Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Abstract Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C–C bond formations in organic molecules. In the present research work novel derivatives of 2,5-dibromo-3-methylthiophene (3a–k and 3l–p) has been synthesized, via Suzuk...

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Bibliographic Details
Main Authors: Komal Rizwan, Muhammad Zubair, Nasir Rasool, Tariq Mahmood, Khurshid Ayub, Noorjahan Banu Alitheen, Muhammad Nazirul Mubin Aziz, Muhammad Nadeem Akhtar, Faiz-ul-Hassan Nasim, Snober Mona Bukhary, Viqar Uddin Ahmad, Mubeen Rani
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Chemistry Central Journal
Subjects:
Density functional theory
Thiophene
Antioxidant
Antibacterial
Palladium
Online Access:http://link.springer.com/article/10.1186/s13065-018-0404-7

Internet

http://link.springer.com/article/10.1186/s13065-018-0404-7

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