Integration of Trypanosoma cruzi kDNA minicircle sequence in the host genome may be associated with autoimmune serum factors in Chagas disease patients

Integration of kDNA sequences within the genome of the host cell shown by PCR amplification with primers to the conserved Trypanosoma cruzi kDNA minicircle sequence was confirmed by Southern hybridization with specific probes. The cells containing the integrated kDNA sequences were then perpetuated...

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Bibliographic Details
Main Authors: Augusto Simões-Barbosa, Ana Maria Barros, Nadjar Nitz, Enrique R Argañaraz, Antonio RL Teixeira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1999-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700041