Inhibitory effects of ursolic acid from Bushen Yijing Formula on TGF-β1-induced human umbilical vein endothelial cell fibrosis via AKT/mTOR signaling and Snail gene

Inhibitory effects of ursolic acid from Bushen Yijing Formula on TGF-β1-induced human umbilical vein endothelial cell fibrosis via AKT/mTOR signaling and Snail gene

The present study aimed to investigate the functional components from Bushen Yijing Formula and their inhibition of endothelial–mesenchymal transition (EndMT) and fibrosis in human umbilical vascular endothelial cells (HUVECs). HUVEC fibrosis was induced by treatment of transforming growth factor β...

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Bibliographic Details
Main Authors: Ke Zhu, Cuixiang Cao, Jiaqi Huang, Zixuan Cheng, Donghai Li, Xiuting Liu, Yueping Mao, Qing Qi
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319300374

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http://www.sciencedirect.com/science/article/pii/S1347861319300374

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