Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences.

BACKGROUND AND PURPOSE:Withanolides are naturally occurring chemical compounds. They are secondary metabolites produced via oxidation of steroids and structurally consist of a steroid-backbone bound to a lactone or its derivatives. They are known to protect plants against herbivores and have medicin...

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Main Authors: Kirti Vaishnavi, Nishant Saxena, Navjot Shah, Rumani Singh, Kavyashree Manjunath, M Uthayakumar, Shankar P Kanaujia, Sunil C Kaul, Kanagaraj Sekar, Renu Wadhwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3433425?pdf=render