TEM ExosomeAnalyzer: a computer-assisted software tool for quantitative evaluation of extracellular vesicles in transmission electron microscopy images

TEM ExosomeAnalyzer: a computer-assisted software tool for quantitative evaluation of extracellular vesicles in transmission electron microscopy images

Extracellular vesicles (EVs) function as important conveyers of information between cells and thus can be exploited as drug delivery systems or disease biomarkers. Transmission electron microscopy (TEM) remains the gold standard method for visualisation of EVs, however the analysis of individual EVs...

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Bibliographic Details
Main Authors: Anna Kotrbová, Karel Štěpka, Martin Maška, Jakub Jozef Pálenik, Ladislav Ilkovics, Dobromila Klemová, Marek Kravec, František Hubatka, Zankruti Dave, Aleš Hampl, Vítězslav Bryja, Pavel Matula, Vendula Pospíchalová
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
exosome
transmission electron microscopy
negative staining
cryo-electron microscopy
extracellular vesicles
semi-automatic detection
segmentation
image analysis
morphological seeded watershed
size distribution profile
Online Access:http://dx.doi.org/10.1080/20013078.2018.1560808

Internet

http://dx.doi.org/10.1080/20013078.2018.1560808

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