Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome

Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome

Background: Genes involved in Tourette syndrome (TS) remain largely unknown. We aimed to identify genetic factors contributing to TS in a French cohort of 120 individuals using a combination of hypothesis-driven and exome-sequencing approaches. Methods: We first sequenced exons of SLITRK1-6 and HDC...

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Bibliographic Details
Main Authors: Christel Depienne, Sorana Ciura, Oriane Trouillard, Delphine Bouteiller, Elsa Leitã;o, Caroline Nava, Boris Keren, Yannick Marie, Justine Guegan, Sylvie Forlani, Alexis Brice, Mathieu Anheim, Yves Agid, Paul Krack, Philippe Damier, François Viallet, Jean-Luc Houeto, Franck Durif, Marie Vidailhet, Yulia Worbe, Emmanuel Roze, Edor Kabashi, Andreas Hartmann
Format: Article
Language:English
Published: Ubiquity Press 2019-11-01
Series:Tremor and Other Hyperkinetic Movements
Subjects:
tourette syndrome
gene
variant
susceptibility factor
opioid receptor
zebrafish
oprk1
Online Access:https://tremorjournal.org/index.php/tremor/article/view/693/2487

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https://tremorjournal.org/index.php/tremor/article/view/693/2487

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