Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

Myelination depends on timely, precise control of oligodendrocyte differentiation and myelinogenesis. Cholesterol is the most abundant component of myelin and essential for myelin membrane assembly in the central nervous system. However, the underlying mechanisms of precise control of cholesterol bi...

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Bibliographic Details
Main Authors: Xin Zhou, Seula Shin, Chenxi He, Qiang Zhang, Matthew N Rasband, Jiangong Ren, Congxin Dai, Rocío I Zorrilla-Veloz, Takashi Shingu, Liang Yuan, Yunfei Wang, Yiwen Chen, Fei Lan, Jian Hu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
cholesterol biosynthesis
myelination
Qki
Srebp2
Online Access:https://elifesciences.org/articles/60467

Internet

https://elifesciences.org/articles/60467

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