Modulation of GSK-3 as a therapeutic strategy on Tau pathologies

Glycogen synthase kinase 3 (GSK-3) is ubiquitously expressed and unusually active in resting, non-stimulated cells. In mammals, at least three proteins (,  and generated from two different genes, gsk3 and gsk3 are widely expressed at both the RNA and protein levels although some tissues...

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Bibliographic Details
Main Authors: Miguel eMedina, Juan Jose eGarrido, Francisco G Wandosell
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2011.00024/full