New Crambescidin-Type Alkaloids from the Indonesian Marine Sponge Clathria bulbotoxa

A crude methanolic extract of the Indonesian sponge Clathria bulbotoxa showed a potent cytotoxic activity against the human epidermoid carcinoma A431 cells. An investigation of the active components led to the isolation of three new compounds named crambescidins 345 (1), 361 (2), and 373 (3), togeth...

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Bibliographic Details
Main Authors: Kasmiati Kasmiati, Yukio Yoshioka, Tetsuji Okamoto, Makoto Ojika
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/3/84