MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

The conserved MICOS complex functions as a primary determinant of mitochondrial inner membrane structure. We address the organization and functional roles of MICOS and identify two independent MICOS subcomplexes: Mic27/Mic10/Mic12, whose assembly is dependent on respiratory complexes and the mitocho...

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Bibliographic Details
Main Authors: Jonathan R Friedman, Arnaud Mourier, Justin Yamada, J Michael McCaffery, Jodi Nunnari
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
mitochondria
MICOS
cristae
respiratory complex
cardiolipin
Online Access:https://elifesciences.org/articles/07739

Internet

https://elifesciences.org/articles/07739

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