Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardiolipin Synthesis

Bacillus anthracis Responds to Targocil-Induced Envelope Damage through EdsRS Activation of Cardiolipin Synthesis

Compromising the integrity of the bacterial cell barrier is a common action of antimicrobials. Targocil is an antimicrobial that is active against the bacterial envelope. We hypothesized that Bacillus anthracis, a potential weapon of bioterror, senses and responds to targocil to alleviate targocil-d...

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Bibliographic Details
Main Authors: Clare L. Laut, William J. Perry, Alexander L. Metzger, Andy Weiss, Devin L. Stauff, Suzanne Walker, Richard M. Caprioli, Eric P. Skaar
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mBio
Subjects:
bacillus anthracis
antimicrobial agents
cell envelope
phospholipids
two-component regulatory systems
Online Access:https://doi.org/10.1128/mBio.03375-19

Internet

https://doi.org/10.1128/mBio.03375-19

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