Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy

<p>Abstract</p> <p>Background</p> <p>We aimed to clarify whether soluble CD40 ligand (sCD40L) activated B cells may be loaded with HBcAg18-27 peptide and served as antigen-producing cells (APCs) to induce HBV-specific cytolytic T lymphocytes (CTLs).</p> <p>R...

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Bibliographic Details
Main Authors: Yan Xiaomin, Chen Junhao, Chen Guangmei, Zhao Qi, Liu Yong, Wu Chao, Zhou Yi-Hua, Huang Zuhu
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/370