Sensitization of neonatal rat lumbar motoneuron by the inflammatory pain mediator bradykinin

Bradykinin (Bk) is a potent inflammatory mediator that causes hyperalgesia. The action of Bk on the sensory system is well documented but its effects on motoneurons, the final pathway of the motor system, are unknown. By a combination of patch-clamp recordings and two-photon calcium imaging, we foun...

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Bibliographic Details
Main Authors: Mouloud Bouhadfane, Attila Kaszás, Balázs Rózsa, Ronald M Harris-Warrick, Laurent Vinay, Frédéric Brocard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06195