Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients

Virus-triggered exacerbation in allergic asthmatic children: neutrophilic airway inflammation and alteration of virus sensors characterize a subgroup of patients

Abstract Background Viruses are important triggers of asthma exacerbations. They are also detected outside of exacerbation. Alteration of anti-viral response in asthmatic patients has been shown although the mechanisms responsible for this defect remain unclear. The objective of this study was to co...

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Bibliographic Details
Main Authors: Antoine Deschildre, Muriel Pichavant, Ilka Engelmann, Carole Langlois, Elodie Drumez, Guillaume Pouessel, Sophie Boileau, David Romero-Cubero, Irina Decleyre-Badiu, Anny Dewilde, Didier Hober, Véronique Néve, Caroline Thumerelle, Stéphanie Lejeune, Clémence Mordacq, Philippe Gosset
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Respiratory Research
Subjects:
Allergic asthma
Exacerbation
Viral infection
Pattern recognition receptor
Interferon
Online Access:http://link.springer.com/article/10.1186/s12931-017-0672-0

Internet

http://link.springer.com/article/10.1186/s12931-017-0672-0

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