Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy

Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy

Abstract Aims The abundance of beta 3‐adrenergic receptors (β3‐ARs) is upregulated in diseased human myocardium. We previously showed that cardiac‐specific expression of β3‐AR inhibits the hypertrophic response to neurohormonal stimulation. Here, we further analysed signalling pathways involved in t...

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Bibliographic Details
Main Authors: Emilie Dubois‐Deruy, Roselle Gelinas, Christophe Beauloye, Hrag Esfahani, Lauriane Y.M. Michel, Chantal Dessy, Luc Bertrand, Jean‐Luc Balligand
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:ESC Heart Failure
Subjects:
Adrenergic receptor
AMP‐activated kinase (AMPK)
Autophagy
Heart failure
Cardiac hypertrophy
Online Access:https://doi.org/10.1002/ehf2.12648

Internet

https://doi.org/10.1002/ehf2.12648

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