Human Aquaporin 4 Gene Polymorphisms and Haplotypes Are Associated With Serum S100B Level and Negative Symptoms of Schizophrenia in a Southern Chinese Han Population

Human Aquaporin 4 Gene Polymorphisms and Haplotypes Are Associated With Serum S100B Level and Negative Symptoms of Schizophrenia in a Southern Chinese Han Population

Background: Aquaporin 4 (AQP4) polymorphism may influence the required dosage of antipsychotic drugs. However, the roles of AQP4 polymorphisms in the blood—brain barrier (BBB) and different neuroprotective effects need further exploration. This study aims to investigate whether the gene polymorphism...

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Bibliographic Details
Main Authors: Yung-Fu Wu, Huey-Kang Sytwu, For-Wey Lung
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Psychiatry
Subjects:
schizophrenia (SCZ)
aquaporin 4 (AQP4)
single nucleotide polymorphism (SNP)
haplotype
S100 calcium-binding protein B (S100B)
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00657/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00657/full

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