RGD Peptides-Conjugated Pluronic Triblock Copolymers Encapsulated with AP-2α Expression Plasmid for Targeting Gastric Cancer Therapy in Vitro and in Vivo

RGD Peptides-Conjugated Pluronic Triblock Copolymers Encapsulated with AP-2α Expression Plasmid for Targeting Gastric Cancer Therapy in Vitro and in Vivo

Gastric cancer, a high-risk malignancy, is a genetic disease developing from a cooperation of multiple gene mutations and a multistep process. Gene therapy is a novel treatment method for treating gastric cancer. Here, we developed a novel Arg-Gly-Asp (RGD) peptides conjugated copolymers nanopartic...

Full description

Bibliographic Details
Main Authors: Wei Wang, Zhimin Liu, Peng Sun, Cheng Fang, Hongwei Fang, Yueming Wang, Jiajia Ji, Jun Chen
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
gastric cancer
gene therapy
triblock copolymers
AP-2α
RGD
Online Access:http://www.mdpi.com/1422-0067/16/7/16263

Internet

http://www.mdpi.com/1422-0067/16/7/16263

Similar Items