Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART.

Whereas cells productively infected with human immunodeficiency virus type 1 (HIV-1) decay rapidly in the setting of highly active antiretroviral therapy (HAART), latently infected resting CD4(+) T cells decay very slowly, persisting for the lifetime of the patient and thus forming a stable reservoi...

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Bibliographic Details
Main Authors: Ahmad R Sedaghat, Janet D Siliciano, Timothy P Brennan, Claus O Wilke, Robert F Siliciano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1959378?pdf=render