The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65.

The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65.

Porphyromonas gingivalis is a major pathogen in severe and chronic manifestations of periodontal disease, which is one of the most common infections of humans. A central feature of P. gingivalis pathogenicity is dysregulation of innate immunity at the gingival epithelial interface, including suppres...

Full description

Bibliographic Details
Main Authors: Hiroki Takeuchi, Takanori Hirano, Sarah E Whitmore, Ichijiro Morisaki, Atsuo Amano, Richard J Lamont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3630210?pdf=render

Internet

http://europepmc.org/articles/PMC3630210?pdf=render

Similar Items